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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA6 All Species: 19.39
Human Site: Y746 Identified Species: 42.67
UniProt: Q8N139 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N139 NP_525023.2 1617 184286 Y746 E N K E K L V Y T L P L E R T
Chimpanzee Pan troglodytes XP_001146278 1564 178469 D705 E R T N T F P D L F S D L D K
Rhesus Macaque Macaca mulatta XP_001083010 1618 184304 Y747 K N K E K L V Y T L P L E R T
Dog Lupus familis XP_850922 1621 183954 Y745 E N K E K L V Y I L P M E R T
Cat Felis silvestris
Mouse Mus musculus Q8K441 1624 183252 Y746 K T K E K L V Y I L P L E R T
Rat Rattus norvegicus Q8CF82 1642 185792 Y746 Q N D Q Q I V Y S L P F K D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509469 1722 195635 Y826 Q T E Q Q L V Y S L P F K D M
Chicken Gallus gallus XP_415691 1546 175373 F704 V N K F P D L F R G L D N C S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001092716 1654 185619 F749 Q Q E A E L T F T L P F E S M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 Q810 E R G E M H G Q Q I E I I L P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 K815 V G N E I S F K L P L A S L P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.4 94.8 74.9 N.A. 67.3 40.7 N.A. 39.2 44 N.A. 40.5 N.A. N.A. N.A. 22.7 N.A.
Protein Similarity: 100 96.2 96.9 84.5 N.A. 80.7 61 N.A. 59.2 62.4 N.A. 61 N.A. N.A. N.A. 43.5 N.A.
P-Site Identity: 100 6.6 93.3 86.6 N.A. 80 33.3 N.A. 33.3 13.3 N.A. 33.3 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 6.6 100 93.3 N.A. 86.6 73.3 N.A. 73.3 33.3 N.A. 60 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 10 0 0 10 0 10 0 0 0 19 0 28 0 % D
% Glu: 37 0 19 55 10 0 0 0 0 0 10 0 46 0 0 % E
% Phe: 0 0 0 10 0 10 10 19 0 10 0 28 0 0 0 % F
% Gly: 0 10 10 0 0 0 10 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 0 19 10 0 10 10 0 0 % I
% Lys: 19 0 46 0 37 0 0 10 0 0 0 0 19 0 10 % K
% Leu: 0 0 0 0 0 55 10 0 19 64 19 28 10 19 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 28 % M
% Asn: 0 46 10 10 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 10 0 10 0 0 10 64 0 0 0 19 % P
% Gln: 28 10 0 19 19 0 0 10 10 0 0 0 0 0 0 % Q
% Arg: 0 19 0 0 0 0 0 0 10 0 0 0 0 37 0 % R
% Ser: 0 0 0 0 0 10 0 0 19 0 10 0 10 10 10 % S
% Thr: 0 19 10 0 10 0 10 0 28 0 0 0 0 0 37 % T
% Val: 19 0 0 0 0 0 55 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 55 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _